Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6518929
Normalized Enrichment Score (NES)	-1.5623447
Nominal p-value	0.0050251256
FDR q-value	0.17827597
FWER p-Value	0.823

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CD8B	1940411 2570035	797	0.856	-0.0203	No
2	STAT5A	2680458	844	0.819	-0.0011	No
3	IL12RB1	2230338 5420053	1099	0.628	0.0018	No
4	TBX21	5270594	1422	0.489	-0.0026	No
5	CYLD	6590079	1543	0.439	0.0026	No
6	TYK2	1660465 1740736	1638	0.411	0.0085	No
7	IL12RB2	6020465	1740	0.379	0.0131	No
8	TGFB1	1940162	1890	0.338	0.0140	No
9	BCL3	3990440	1936	0.326	0.0202	No
10	STAT6	1190010 5720019	2231	0.254	0.0111	No
11	IL2RA	6620450	2288	0.238	0.0144	No
12	UBE2D3	3190452	2324	0.231	0.0186	No
13	NFKB1	5420358	2339	0.229	0.0239	No
14	RAB7A	450433 4070112 4480324	2361	0.224	0.0287	No
15	GADD45G	2510142	2606	0.179	0.0203	No
16	CCL3	2810092	2939	0.135	0.0060	No
17	CD80	870112	2970	0.133	0.0079	No
18	STAT4	1660373 3130019	3084	0.122	0.0050	No
19	TNF	6650603	3230	0.108	0.0001	No
20	IL12A	7100551	3313	0.100	-0.0017	No
21	IL27RA	940093	3353	0.097	-0.0012	No
22	CCL4	50368 430047	3379	0.094	-0.0001	No
23	MALT1	4670292	3761	0.066	-0.0189	No
24	PRKCA	6400551	3810	0.064	-0.0198	No
25	REL	360707	3994	0.055	-0.0283	No
26	JAK2	3780528 6100692 6550577	4011	0.054	-0.0277	No
27	IL1B	2640364	4444	0.039	-0.0500	No
28	BIRC2	2940435 4730020	4458	0.039	-0.0497	No
29	IL1R1	3850377 6180128	4746	0.032	-0.0643	No
30	IL13	7040021	5301	0.023	-0.0936	No
31	RIPK2	5050072 6290632	5362	0.023	-0.0963	No
32	IL4	6020537	5571	0.020	-0.1070	No
33	IL12B	460008	6012	0.016	-0.1303	No
34	ATM	3610110 4050524	6095	0.015	-0.1343	No
35	GZMA	3390315	6453	0.013	-0.1533	No
36	PIAS2	1690301 5900647	7123	0.009	-0.1892	No
37	PIK3R1	4730671	7181	0.009	-0.1920	No
38	RAN	2260446 4590647	7473	0.008	-0.2075	No
39	XPO1	540707	8292	0.005	-0.2516	No
40	ARRB2	2060441	9730	-0.000	-0.3292	No
41	PIK3CA	6220129	9883	-0.001	-0.3374	No
42	IL6	380133	10180	-0.001	-0.3534	No
43	CCR5	1980072 5910722	10369	-0.002	-0.3635	No
44	IL27	1990324	10986	-0.004	-0.3966	No
45	SRC	580132	11138	-0.004	-0.4047	No
46	NOD2	2510050	11439	-0.006	-0.4207	No
47	GZMB	380066	11641	-0.006	-0.4314	No
48	IL2	1770725	11670	-0.006	-0.4328	No
49	B2M	5080332 5130059	11781	-0.007	-0.4385	No
50	FBXW11	6450632	11943	-0.008	-0.4470	No
51	IL18	6180039	11993	-0.008	-0.4494	No
52	IL18RAP	3850088	12273	-0.009	-0.4643	No
53	CHUK	7050736	12475	-0.010	-0.4749	No
54	IFNG	5670592	13089	-0.014	-0.5076	No
55	SYK	6940133	13759	-0.022	-0.5432	No
56	IL17A	4280369	14282	-0.031	-0.5705	No
57	FRAP1	2850037 6660010	14456	-0.034	-0.5790	No
58	JUN	840170	14517	-0.036	-0.5813	No
59	MAP2K3	5570193	14524	-0.036	-0.5806	No
60	ETV5	110017	14646	-0.040	-0.5861	No
61	ERC1	1580170 2630717 6110762 6840280	14833	-0.047	-0.5949	No
62	FOS	1850315	14961	-0.053	-0.6004	No
63	FASLG	2810044	15184	-0.066	-0.6106	No
64	PRF1	6660309	15276	-0.071	-0.6137	No
65	IKBKG	3450092 3840377 6590592	15354	-0.077	-0.6158	No
66	IKBKB	6840072	15396	-0.080	-0.6159	No
67	CREBBP	5690035 7040050	15556	-0.095	-0.6220	No
68	IL18R1	270546	15602	-0.100	-0.6217	No
69	CD86	3390471 6200280	15717	-0.111	-0.6249	No
70	ATF2	2260348 2480441	15731	-0.113	-0.6226	No
71	IRF1	2340152 3450592 6290121 6980577	15795	-0.121	-0.6228	No
72	EOMES	2100707	15884	-0.131	-0.6241	No
73	EBI3	5340300	16018	-0.150	-0.6273	No
74	MAPK8	2640195	16060	-0.156	-0.6254	No
75	JAK1	5910746	16124	-0.165	-0.6244	No
76	IL2RB	4730072	16634	-0.253	-0.6452	Yes
77	GADD45B	2350408	16698	-0.265	-0.6415	Yes
78	NFKB2	2320670	16848	-0.300	-0.6416	Yes
79	MAPK14	5290731	16936	-0.320	-0.6378	Yes
80	RELA	3830075	16981	-0.335	-0.6313	Yes
81	RELB	1400048	17053	-0.356	-0.6257	Yes
82	TRAF6	4810292 6200132	17300	-0.454	-0.6269	Yes
83	LCK	3360142	17374	-0.493	-0.6178	Yes
84	MAP3K14	5890435	17378	-0.493	-0.6049	Yes
85	STAT2	3780519	17400	-0.501	-0.5927	Yes
86	MAP2K6	1230056 2940204	17578	-0.578	-0.5869	Yes
87	GATA3	6130068	17582	-0.581	-0.5716	Yes
88	IL6ST	5890047	17666	-0.627	-0.5595	Yes
89	CD3D	2810739	17668	-0.628	-0.5429	Yes
90	BCL10	2360397	17750	-0.680	-0.5292	Yes
91	NFKBIA	1570152	17914	-0.797	-0.5168	Yes
92	STAT3	460040 3710341	17921	-0.802	-0.4958	Yes
93	CD4	1090010	17959	-0.836	-0.4757	Yes
94	STAT1	6510204 6590553	18002	-0.879	-0.4546	Yes
95	IL2RG	4120273	18120	-1.031	-0.4335	Yes
96	SOCS1	730139	18178	-1.112	-0.4071	Yes
97	CD3E	3800056	18183	-1.120	-0.3776	Yes
98	MAPK9	2060273 3780209 4070397	18415	-1.759	-0.3434	Yes
99	SPHK2	2030487 4120670 4850114	18429	-1.804	-0.2962	Yes
100	CD28	1400739 4210093	18442	-1.868	-0.2473	Yes
101	CD3G	2680288	18446	-1.891	-0.1973	Yes
102	CD247	3800725 5720136	18447	-1.894	-0.1470	Yes
103	TNFAIP3	2900142	18472	-2.065	-0.0935	Yes
104	TNFRSF1A	1090390 6520735	18601	-3.812	0.0008	Yes